Teaching Responsibility
LJMU Schools involved in Delivery:
Pharmacy & Biomolecular Sciences
Learning Methods
Lecture
Practical
Workshop
Module Offerings
7121PHASCI-JAN-CTY
Aims
To provide students with knowledge and skills to master the principles of pharmaceutical formulation and advanced drug delivery methods.
Learning Outcomes
1.
Demonstrate expertise in applying the principles of pharmaceutical formulation in the design of advanced drug delivery systems
2.
Formulate and evaluate a pharmaceutical delivery system.
3.
Display mastery of interpreting complex information and data in the evaluation of advanced drug systems
Module Content
Outline Syllabus:Introduction to the basic components of formulation, delivery systems (nanoparticles, tablets, capsules, etc.) and routes of delivery (oral, buccal, parenteral, pulmonary, nasal, topical, transdermal).
Immediate and modified release systems: excipients and polymers; immediate release formulations; modified release formulations; oral and buccal delivery; fast disintegrating tablets and enteric coatings etc; Paediatric delivery.
Nanoformulation; nanomedicines; biodegradable polymers; polymeric micro/nanoparticles; lipid-based nanoparticles; parenteral and pulmonary delivery; targeted delivery; cancer therapy.
Challenges in biopharmaceutical delivery: proteins, vaccines, genes; biomolecule stability, bioavailability and first pass metabolism; solutions, nanoparticles and lipid carriers; Routes of delivery; insulin and vaccine delivery.
Special topics and future developments supported by recent literature. For example; clays for drug delivery, wound healing, nanoparticles for medical diagnosis.
Mini-project: Group project to design, produce and evaluate a delivery system for an assigned API.
Module Overview:
This module will provide you with knowledge and skills to master the principles of pharmaceutical formulation and advanced drug delivery methods.
This module will provide you with knowledge and skills to master the principles of pharmaceutical formulation and advanced drug delivery methods.
Additional Information:Practical sessions will involve students developing hands-on experience of formulating and evaluating delivery systems.
Exam will assess students understanding of the principles through data interpretation and problem solving questions
Assessments
Centralised Exam
Portfolio