Teaching Responsibility
LJMU Schools involved in Delivery:
Pharmacy & Biomolecular Sciences
Learning Methods
Lecture
Practical
Workshop
Module Offerings
5111BMBMOL-SEP-CTY
Aims
An introduction to the practical and theoretical concepts of medical microbiology and immunology.
To provide an understanding of the principles and practices involved in the laboratory diagnosis, prevention and treatment of infectious diseases in humans.
Learning Outcomes
1.
Apply knowledge of cellular and humoral components of the immune response and selected immunological techniques
2.
Apply knowledge in the identification of pathogenic organisms and in the treatment of infectious disease
3.
Review the principles of vaccination and the role of immunity in infectious diseases
4.
Apply knowledge of the range of microorganisms involved in human disease
processes and the role of normal microbiota in health and disease
Module Content
Outline Syllabus:Microorganisms involved in human disease and mechanisms of pathogenicity. Public Health microbiology.
Clinical specimens used in the diagnosis and prevention of infectious disease together with an appreciation of normal microbiota contaminants.
The importance of microbial culture and microscopy procedures for the isolation and identification of suspected pathogens. Biochemical, serological and molecular methods used in identification of bacteria and viruses.
The modes of action of selected antimicrobial and anti-viral chemotherapeutic agents together with methods for determining their effectiveness and potential toxicity. The emergence of bacterial resistance and the value of drug resistance epidemiology.
Overview of Immunity: concepts of self and non-self, innate and adaptive immunity, acute and chronic inflammation, immune surveillance and tolerance, specificity and diversity of immune response. primary and secondary responses.
Immune cells and tissues.
Humoral immunity: antibody structure and function, primary and secondary responses, antigen-antibody interactions, complement, acute phase reactions, cytokines..
Cellular immunity: B and T cell receptors and the MHC; antigen presentation, clonal expansion, concepts of immunological memory
Selected immunological techniques,
Vaccination: active and passive immunisation
Role of immune system in defence processes (e.g. elimination of microorganisms, tumour surveillance, induction of inflammation) and as a therapeutic tool.
Introduction to immune dysfunction (e.g. hypersensitivity, autoimmunity, immunodeficiency) and immunity in pregnancy; case studies of selected diseases including diagnosis and therapy. The immune system and cancer.
Prophylaxis and immunotherapy
Module Overview:
This module provides an introduction to the practical and theoretical concepts of medical microbiology and immunology. It will also provide an understanding of the principles and practices involved in the laboratory diagnosis, prevention and treatment of infectious diseases in humans.
This module provides an introduction to the practical and theoretical concepts of medical microbiology and immunology. It will also provide an understanding of the principles and practices involved in the laboratory diagnosis, prevention and treatment of infectious diseases in humans.
Additional Information:Infection and immunity is designed so students may learn and fully appreciate the importance of microorganisms and the immune system in human health and disease. The content is practically orientated in order to develop important skills that may later be appreciated in the workplace environment. Students are encouraged to use reviews, papers and subject specific texts. There is a wide range of medical microbiology and immunology textbooks available. Students should have access to one of each.
Assessments
Portfolio
Test